proteome profiler human apoptosis array kit  (R&D Systems)

Journal: Scientific Reports

Article Title: A natural coumarin, benjaminin, suppresses proliferation and migration and induces apoptosis in MCF-7 breast cancer cells

doi: 10.1038/s41598-026-51303-6

Figure Lengend Snippet: Effects of benjaminin on apoptosis activation and apoptotic protein levels following 24 h of treatment with 0.1% DMSO (control) or benjaminin (IC₅₀). Benjaminin increased the proportion of apoptotic cells and modulated apoptotic protein expression. ( a ) Representative cytograms showing cell distribution across apoptotic stages. ( b ) Fold changes in apoptotic protein signal intensity relative to DMSO; lysates were pooled from two independent experiments. Data in ( a ) are mean ± SD of three biological replicates (n = 3). Statistical significance was determined using Student’s t-test. *P < 0.05, **P < 0.001.

Article Snippet: RayBio® Human Apoptosis Array G1 kit was purchased from Raybiotech (USA).

Techniques: Activation Assay, Control, Expressing

Journal: Cell Communication and Signaling : CCS

Article Title: Marine trichodermamide B inhibits prostate cancer progression via catalase inhibition-induced apoptosis

doi: 10.1186/s12964-026-02737-y

Figure Lengend Snippet: Trichodermamide B (TRH2) affects prostate cell cycle and apoptosis in prostate cancer cells. A & B Effect of TRH2 on the cell cycle distribution of LNCaP cells. C & D Effect of TRH2 on the cell cycle distribution of PC-3 cells. E & F The protein expression of Cyclin A2 in LNCaP cells. G & H The protein expression of Cyclin A2 in PC-3 cells. I & J Effect of TRH2 on apoptosis in 22Rv1 cells. K & L Effect of TRH2 on apoptosis in PC-3 cells. * P <0.05, ** P <0.01 vs control

Article Snippet: After treatment with either DMSO (0.1%, v/v) or TRH2 (8 μM) for 48 h, cells were harvested and proteins were extracted and analyzed according to the instructions of the Human Apoptosis Array Kit (Cat# ARY009, R&D Systems).

Techniques: Expressing, Control

Journal: Cell Communication and Signaling : CCS

Article Title: Marine trichodermamide B inhibits prostate cancer progression via catalase inhibition-induced apoptosis

doi: 10.1186/s12964-026-02737-y

Figure Lengend Snippet: Trichodermamide B (TRH2) alters the ultrastructure of prostate cancer cells and modifies the expression of apoptosis-related proteins. A Morphology of normal LNCaP cells under the transmission electron microscope. B & C Morphological changes in LNCaP cells treated with TRH2 under transmission electron microscopy. D & E Effect of TRH2 on the expression of apoptosis-related proteins in LNCaP cells. F & G Effect of TRH2 on the expression of apoptosis-related proteins in PC-3 cells

Article Snippet: After treatment with either DMSO (0.1%, v/v) or TRH2 (8 μM) for 48 h, cells were harvested and proteins were extracted and analyzed according to the instructions of the Human Apoptosis Array Kit (Cat# ARY009, R&D Systems).

Techniques: Expressing, Transmission Assay, Microscopy, Electron Microscopy